Eryngium Billardieri Induces Apoptosis via Bax Gene Expression in Pancreatic Cancer Cells
نویسندگان
چکیده
منابع مشابه
Sodium selenite induces apoptosis in colon cancer cells via Bax-dependent mitochondrial pathway.
OBJECTIVES We aimed to elucidate a possible mechanism of action by investigating the effects of selenium (Se) on cell cycle arrest and apoptosis in colorectal cancer cells (HCT116 cells and SW620 cells). MATERIALS AND METHODS The colorectal cancer cells were treated with varying concentrations of Se (1 microM, 5 microM and 10 microM) for 24 hours. The effects of Se on cell cycle, apoptosis, m...
متن کاملCroton Tiglium Extract Induces Apoptosis via Bax/Bcl-2 Pathways in Human Lung Cancer A549 Cells
Objective: To investigate the impact of a Croton tiglium extract on cellular proliferation and apoptosis in a nonsmall cell lung cancer cell line (A549) in vitro. Methods: A Croton tiglium seed methanol extract was prepare and assessed for effects on A549 cells regarding cellular proliferation, apoptotic rates, and expression of apoptosis related genes and proteins using real-time PCR and immun...
متن کاملOpium Induces Apoptosis in Jurkat Cells
Background: The direct effect of some opioids on immune cells has been demonstrated. The aim of this study was to assess the apoptotic effect of opium on Jurkat T lymphocyte cells. Methods: Different concentrations of opium (2.86 × 10-3 to 2.86 × 10-11 g/ml) were added to 24-well plates containing 5 × 105 Jurkat cells. Apoptotic events were assessed after 6, 24, and 72 hours by flow-cytometric...
متن کاملEconazole Nitrate Induces Apoptosis in MCF-7 Cells via Mitochondrial and Caspase Pathways
Econazole nitrate (EN), a synthetic compound, is now in use as a routine antifungal drug. EN was shown to have antitumor effect, the tumor cell killing mechanisms, however, remain unclear. In this research, the apoptosis-inducing effect of EN on MCF-7 cells was investigated. The results showed that EN inhibited the proliferation of MCF-7 cells in a time- and dose-dependent manner by MTT method ...
متن کاملEconazole Nitrate Induces Apoptosis in MCF-7 Cells via Mitochondrial and Caspase Pathways
Econazole nitrate (EN), a synthetic compound, is now in use as a routine antifungal drug. EN was shown to have antitumor effect, the tumor cell killing mechanisms, however, remain unclear. In this research, the apoptosis-inducing effect of EN on MCF-7 cells was investigated. The results showed that EN inhibited the proliferation of MCF-7 cells in a time- and dose-dependent manner by MTT method ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Advanced Pharmaceutical Bulletin
سال: 2018
ISSN: 2228-5881,2251-7308
DOI: 10.15171/apb.2018.075